PREVENTION OF CSF LEAK FROM THE SPINAL OPERATION SITE DUE TO EITHER TRAUMATIC OR IATROGENIC INJURY TO THE DURA.

Prevention of CSF leak from the spinal operation site due to either traumatic or iatrogenic injury to the Dura.

Background: Cerebrospinal fluid leak is a relatively common problem ranging from 0.5% to 18% with traumatic or incidental injury to the Dura intra-operatively1, 2.Traumatic injury mostly occurs due to mechanical trauma with subsequent thecal sac laceration mainly in the thoracolumbar region.Incidental Dural injury commonly happens in patients under

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Challenges and solutions to the scale-up of porous materials

Abstract With increasing pace, crystalline open frameworks are moving to larger scale, mature applications that hedelm?kori metalli stretch as broadly as catalysis, separation, water purification, adsorption, sensing, biomineralization and energy storage.A particular challenge in this development can be the unexpected variation in material properti

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The Caenorhabditis elegans iodotyrosine deiodinase ortholog SUP-18 functions through a conserved channel SC-box to regulate the muscle two-pore domain potassium channel SUP-9.

Loss-of-function mutations in the Caenorhabditis elegans gene sup-18 suppress the defects in muscle contraction conferred by a gain-of-function mutation in SUP-10, a presumptive regulatory subunit of the SUP-9 two-pore domain K(+) channel associated with muscle membranes.We cloned sup-18 and found that it encodes the C.elegans ortholog of mammalian

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